While the supplement is not FDA-approved for any medical use, it is generally considered safe for adults for short-term use.
Dosage Guidelines
When used as a supplement, valerian is most often made from the roots of the plant, but it can also come from dried stems, other plant materials, or plant extracts. It is available in several different forms, including:
CapsulesTabletsTeasTinctures
No specific preparation or dose is considered best for anxiety. Many studies have focused on dosages between 400 and 600 milligrams per day. It is generally best to start with a low dose and slowly increase the amount until you determine which dose works best for you. It should be taken 30 minutes to two hours before bedtime. Dosage for the treatment of insomnia ranges from 300 to 600 mg of liquid root extract or the equivalent of 2 to 3 g of dried valerian root. Lower dosages are typically used for treating nervous tension and when the root is combined with other supplements.
Effects of Valerian Root for Anxiety
The exact reasons why valerian helps anxiety is not known, but it is believed that valerian root has an impact on the availability of the neurotransmitter gamma-aminobutyric acid GABA in the brain. GABA is an amino acid that works as an inhibitory neurotransmitter in the central nervous system (CNS). In other words, it inhibits nerve transmission, which contributes to a calming effect on the body. Some research suggests valerian root has mild sedative and tranquilizing properties—less than prescription sleep medication. Other studies suggest that valerian root may be helpful for anxiety. However, these studies tend to be small and their result unreliable due to design and methodological flaws. In a 2020 meta-analysis, researchers looked at past research to help determine why some research has shown beneficial effects while others have had no impact. The potential culprit, the researchers suspect, is the variable nature of and quality of the herbal extracts utilized in research. Even though valerian root is used for various problems, there is not enough research evidence to support the herb’s effectiveness. The use of valerian root as a sleep aid is supported by some evidence from clinical trials; however, these studies tend to be small and not conducted with strict standards. However, some people who take the supplement regularly have shared that it makes them feel calm and reduces nervous tension and stress. Physicians who prescribe Valerian root have been surprised to hear positive feedback from their patients.
Medication Interactions
Valerian root may make you feel drowsy if you take it with prescription medications such as:
Barbiturates such as phenobarbitol Benzodiazepines Narcotics such as codeine Over-the-counter cold and sleep remedies Selective serotonin reuptake inhibitors (SSRIs)
You should generally check the package insert and speak with a qualified healthcare professional and/or pharmacist about possible interactions. You should not take valerian root if you are pregnant or nursing or if you have liver disease. If you are taking monoamine oxidase inhibitors (MAOIs), other antidepressants, and certain other classes of medication, Valerian root should be used with caution, and may not be appropriate in those cases.
Associated Risks
Unlike prescription sleep medications, valerian root is not believed to carry a risk of dependency. Sometimes, it is even used to help insomniacs with benzodiazepine withdrawal. However, the supplement should only be used under the supervision of a qualified healthcare professional, and caution should be used if you are taking the supplement for an extended period of time. The U.S. Food and Drug Administration does not regulate the production of herbs and supplements. Most herbs and supplements are not thoroughly tested, and there is no guarantee about the ingredients or safety of the products. It may be wise to consult with your doctor before taking valerian root for social anxiety disorder.
